Colocalization, or the mutual occurrence of a signal in a pair of images. Colocalization analysis is aimed at assessing the extent to which the signal that was induced by the object of interest in a pair of images occurs at the same position and intensity. The degree of colocalization in an image can be quantified by the value of a coefficient, the so-called colocalization measure. The most important coefficients are:
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Correlation coefficient - the so-called Pearson correlation coefficient
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Overlap coefficient - the Pearson coefficient
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Manderson coefficients
Evaluating collocation using the coefficients results in a large reduction in the volume of data - from two images with dimensions of usually hundreds to thousands of pixels, the result is one or two numbers describing the dependence of the mutual occurrence of information in the two images.
